Drug Use Strong Predictor for Postpartum Mental Health Problems

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New research from North Carolina State University and the University of British Columbia finds that a woman’s lifetime history of drug use can help predict whether the woman will suffer from problems with stress and anxiety after childbirth. The finding could help health-care providers screen pregnant women for mental health problems and provide relevant treatment.

“There’s been a lot of attention recently on the need to incorporate mental health screening into prenatal care, and it has largely focused on identifying women who are at risk of postpartum depression,” says Sarah Desmarais, an associate professor of psychology at NC State and co-author of a journal article on the work.

“Our study has two important findings that are relevant to that discussion,” Desmarais says. “First, we found that women are at risk of significant postpartum mental health problems other than depression – stress and anxiety are serious issues that merit attention. Second, by incorporating questions about a woman’s history of drug use, we can help health-care providers more accurately identify women who are at risk of postpartum stress and anxiety – and take steps to provide the necessary care.”

The study was not designed to focus specifically on drug use, but was instead aimed at answering the broader question of whether women’s use of alcohol and drugs at any point in their lifetime predicted mental health challenges after childbirth.

“Historically, a lot of research focused on women’s substance use during pregnancy,” Desmarais says. “We thought that may not be a reliable way of capturing women’s substance use, because women are likely less willing to admit to substance use during pregnancy – they’re concerned about losing parental custody, dealing with social stigma, or biasing their treatment and care. What’s more, pregnancy is not when women begin using drugs or alcohol; that’s something that carries over from a woman’s behavior before pregnancy.”

To examine these issues, researchers used data from interviews with 100 women in British Columbia who had given birth in the previous three months, were largely from higher socioeconomic backgrounds and were not considered at high risk of postpartum mental health problems. The study participants were recruited to join a broad health and wellness study, which was not specifically focused on substance use.

In those interviews, women were asked about their history of alcohol use and their history of drug abuse.

“The key finding is that asking about lifetime drug use really helped us predict whether a woman would experience postpartum mental health problems,” Desmarais says.

“The best predictor of postpartum mental health problems is still whether a woman has a history of mental health problems,” Desmarais adds. “But when you include a history of drug use, the likelihood increases significantly.”

Specifically, prior drug use was associated with heightened symptoms of stress and anxiety after childbirth. Drug use was not associated with postpartum depression, and prior alcohol use was not associated with any postpartum mental health problems.

The paper, “Lifetime substance use as a predictor of postpartum mental health,” is published in the journal Archives of Women’s Mental Health. Lead author of the study is Betty-Shannon Prevatt, a Ph.D. student at NC State. The paper was co-authored by Patricia Janssen of UBC. The work was done with support from the British Columbia Mental Health and Addictions Research Network, the Social Sciences and Humanities Research Council of Canada, and the Michael Smith Foundation for Health Research.

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Note to Editors: The study abstract follows.

“Lifetime substance use as a predictor of postpartum mental health”

Authors: Betty-Shannon Prevatt and Sarah L. Desmarais, North Carolina State University; Patricia A. Janssen, University of British Columbia

Published: Dec. 3, Archives of Women’s Mental Health

DOI: 10.1007/s00737-016-0694-5

Abstract: Postpartum mood disorders (PPMD) affect approximately 10–20% of women and have adverse consequences for both mom and baby. Lifetime substance use has received limited attention in relation to PPMD. The present study examined associations of lifetime alcohol and drug use with postpartum mental health problems. Women (n = 100) within approximately 3 months postpartum (M = 2.01, SD = 1.32) participated in semi-structured interviews querying lifetime substance use, mental health history, and postpartum symptoms of anxiety, stress, posttraumatic stress disorder (PTSD), depression, and obsessive compulsive disorder. The study was conducted in an urban Canadian city from 2009 to 2010. Analyses revealed that lifetime substance use increased the variability explained in postpartum PTSD (p = .011), above and beyond sociodemographic characteristics and mental health history. The same trend, though not significant, was observed for stress (p = .059) and anxiety (p = .070). Lifetime drug use, specifically, was associated with postpartum stress (p = .021) and anxiety (p = .041), whereas lifetime alcohol use was not (ps ≥ .128). Findings suggest that lifetime drug use is associated with PPMD. Future research should examine whether screening for lifetime drug use during antenatal and postpartum care improves identification of women experiencing PPMD.